Publications, original
Department of Surgical sciences/Ophthalmology, Akademiska sjukhuset, SE-751 85 Uppsala
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Revised: 22-10-07

Ophthalmic biophysics, original publications
Year Publication
2020 Sandberg Melin C, Yu Z, Söderberg PG Variance components for PIMD-2p estimation of the optic nerve head and consequences in clinical measurements of glaucoma. Acta Ophthalmol 2019; Volume missing: Epub, 1-5
2019 Sandberg Melin C, Malmberg FM, Söderberg PG A strategy for OCT estimation of the optic nerve head pigment epithelium central limit-Inner limit of the retina minimal distance, PIMD-2pi Acta Ophthalmol 2019;97: 208-213, DOI:10.1111/aos.13908
2017 Galichanin K Exposure to subthreshold dose of UVR-B induces apoptosis in the lens epithelial cells and does not in the lens fibre cells. Acta Ophthalmol 2017; 95: 834-838
2017 Yu Z, Talebizadeh N, Kronschläger M, Söderberg PG Measuring temperature in the lens during experimental heat load indirectly as light scattering increase rate JBO 2017;22: 015005-1- 015005-5, DOI:10.1117/1.JBO.22.1.015005
2017 Talebizadeh N, Zhou Hagström NZ, Yu Z, Kronschläger M, Söderberg PG, Wählby CW Objective automated quantification of fluorescence signal in histological sections of rat lens. Cytometry Part A 2017, DOI: 10.1002/cyto.a.23131
2016 Sandberg-Melin C, Nuija EN, Alm A, Yu Z, Söderberg PG Variance components in confocal scanning laser tomography measurements of neuro-retinal rim area and the effect of repeated measurements on the power to detect loss over time Acta Ophthalmol 2016;94: 705-711, DOI:10.1111/aos.13079
2015 Kronschläger M, Talebizadeh N, Yu Z, Meyer LM, Löfgren S Apoptosis in the rat cornea after in vivo exposure to UVR at 300 nm. Cornea 2015; 34: 945-949
2015 Mathew JM, Goosey JG, Söderberg PG, Bergmanson JPG Lamellar Changes in the Keratoconic Cornea Acta Ophthalmol 2015;93: 767-773, DOI:10.1111/aos.12811
2015 Yu Z, Schulmeister K, Talebizadeh N, Kronschläger M, Söderberg PG Temperature controlled in vivo ocular exposure to 1090 nm radiation suggests that near infrared radiation cataract is thermally induced JBO 2015;20: 015003-1 - 015003-4, DOI:10.1117/1.JBO.20.1.015003
2015 Talebizadeh N, Yu Z, Kronschläger M, Hallböök F, Söderberg PG Specific spatial distribution of caspase-3 in normal lenses Acta Ophthalmol 2015;93: 289-292, DOI:10.1111/aos.12501
2015 Yu Z, Schulmeister K, Talebizadeh N, Kronschläger M, Söderberg PG 1090 nm infrared radiation at close to threshold dose induces cataract with a time delay Acta Ophthalmol 2015;93: E118-E122, DOI:10.1111/aos.12508
2014 Kronschläger M, Yu Z, Talebizadeh N, Meyer LM, Söderberg PG Topically applied caffeine induces miosis in the ketamine/xylazine anesthetized rat Exp Eye Res 2014;127: 179-183, DOI:10.1016/j.exer.2014.07.023
2014 Galichanin K, Löfgren S, Söderberg PG Cataract after repeated daily in vivo exposure to ultraviolet radiation Health physics 2014;107: 523-529, DOI:10.1097/HP.0000000000000152.
2014 Yu Z, Persson R, Öhgren JÖ, Sandberg S, Hörberg U, Berglund F, Karlsson K, Steinvall O, Söderberg PG Green light laser exposure at 532nm near the exposure limit during a human volunteer vehicle driving task does not alter structure or function in the visual system. J Laser Appl 2014, DOI: 10.2351/1.4868689
2014 Talebizadeh N, Yu Z, Kronschläger M, Söderberg PG Time evolution of active caspase-3 labelling after in vivo exposure to UVR-300 nm Acta Ophthalmol 2014;92: 769-773, DOI:10.1111/aos.12407
2014 Galichanin K, Yu Z, Söderberg PG Up regulation of GADD45-alpha, TP53 and CASP3 mRNA expression in the rat lens after in vivo exposure to sub-threshold dose of UVR B J Ocular Biology 2014;2: 1-5, DOI:JOCB-2334-2838-02-0016
2014 Kronschläger M, Forsman E, Yu Z, Talebizadeh N, Löfgren S, Meyer LM, Bergquist J, Söderberg PG Pharmacokinetics for topically applied caffeine in the rat Exp Eye Res 2014;122: 94-101, DOI:10.1016/j.exer.2014.03.009
2014 Yu Z, Schulmeister K, Talebizadeh N, Kronschläger M, Söderberg PG Ocular temperature elevation induced by threshold in vivo exposure to 1090-nm infrared radiation and associated heat diffusion JBO 2014;Epub 19: 105008-1- 105008-6, DOI:10.1117/1.JBO.19.10.105008
2014 Meyer LM, Wegener A, Holz F, Kronschläger M, Bergmanson JPG, Söderberg PG Ultrastructure of UVR-B-induced cataract and repair visualized with electron microscopy Acta Ophthalmol 2014;92: 635-643, DOI:10.1111/aos.12376
2014 Talebizadeh N, Yu Z, Kronschläger M, Söderberg PG Modelling the time evolution of active caspase-3 protein in the rat lens after in vivo exposure to ultraviolet radiation-B PLOS one 2014;9: e106926, DOI:10.1371/journal.pone.0106926
2013 Kronschläger M, Yu Z, Talebizadeh N, Meyer LM, Hallböök F, Söderberg PG Evolution of TUNEL-labeling in the Rat Lens After In Vivo Exposure to Just Above Threshold Dose UVB Curr Eye Res 2013;38: 880-885, DOI:doi:10.3109/02713683.2013.783079
2013 Meyer LM, Löfgren S, Holz F, Wegener A, Söderberg PG Bilateral cataract induced by unilateral UVR-B exposure- evidence for an inflammatory response Acta Ophthalmol 2013;91: 236-242, DOI:10.1111/j.1755-3768.2012.02384.x
2013 Mar-Zoega GM, Arnarsson A, Sasaki H, Söderberg PG, Jonasson F The 7-year cumulative incidence of cornea guttata and morphological changes in the corneal endothelium in the Reykjavik Eye Study Acta Ophthalmol 2013;91: 212-218, DOI:10.1111/j.1755-3768.2011.02360.x ...
2013 Kronschläger M, Löfgren S, Yu Z, Talebizadeh N, Varma S, Söderberg PG Caffeine eye drops protect against UV-B cataract Exp Eye Res 2013;113: 26-31, DOI:10.1016/j.exer.2013.04.015
2012 Galichanin K, Svedlund J, Söderberg PG Kinetics of GADD45a, TP53 and CASP3 gene expression in the rat lens in vivo in response to exposure to double threshold dose of UV-B radiation Exp Eye Res 2012;97: 19-23, DOI:10.1016/j.exer.2012.02.003
2012 Söderberg AC, Algvere P, Hengstler J, Seregard S, Söderberg PG, Kvanta A Combination therapy with low-dose transpupillary thermotherapy and intravitreal ranibizumab for neovascular age-related macular degeneration: a 24-month prospective randomised clinical study. Br J Ophthalmol 2012, DOI: 10.1136/bjophthalmol-2011-300721
2012 Kronschläger M, Galichanin K, Ekström J, Lou M, Söderberg PG Protective effect of the thioltransferase gene on in vivo UVR-300 nm-induced cataract. IOVS 2012;53: 248-252, DOI:10.1167/iovs.11-8504
2012 Lee RM, Cuthbertson FM, Söderberg PG, Liu CS A possible strategy for implanting blue-blocking intraocular lenses Acta Ophthalmol 2012;53: e151, DOI:10.1111/j.1755-3768.2011.02166.x.
2012 Mody V, Kakar M, Löfgren S, Söderberg PG High lenticular tolerance to ultraviolet radiation-B by pigmented guinea-pig; application of a safety limit strategy for UVR-induced cataract. Acta Ophthalmol 2012, DOI: 10.1111/j.1755-3768.2010.01931.x
2012 Löfgren S, Michael R, Söderberg PG Impact of iris pigment and pupil size in ultraviolet radiation cataract in rat Acta Ophthalmol 2012;90: 44-48, DOI:10.1111/j.1755-3768.2010.01871.x
2012 Galichanin K, Talebizadeh N, Söderberg PG Characterization of molecular mechanisms of in vivo UVR induced cataract J Vis Exp 2012;69: e4016, DOI:10.3791/4016
2011 Wang J, Dong X, Galichanin K, Söderberg PG Dose-response Relationship for alpha-tocopherol Prevention of Ultraviolet Radiation Induced Cataract in Rat. Exp Eye Res 2011;93: 91-97, DOI:10.1016/j.exer.2011.05.002.
2011 Galichanin K, Wang J, Löfgren S, Söderberg PG A new universal rat restrainer for ophthalmic research. Acta Ophthalmol 2011;89: e67-71, DOI:10.1111/j.1755-3768.2010.01874.x
2011 Bucht C, Söderberg PG, Manneberg G Simulation of specular microscopy images of corneal endothelium, a tool for control of measurement errors. Acta Ophthalmol 2011;89: e242-50, DOI:10.1111/j.1755-3768.2010.01974.x
2010 Wang J, Löfgren S, Dong X, Galichanin K, Söderberg PG Evolution of light scattering and redox balance in the rat lens after in vivo exposure to close to threshold dose ultraviolet radiation. Acta Ophthalmol 2010;88: 779-785, DOI:10.1111/j.1755-3768.2009.01826.x
2010 Galichanin K, Löfgren S, Bergmanson JPG, Söderberg PG Evolution of damage in the lens after in vivo close to threshold exposure to UV-B radiation: cytomorphological study of apoptosis. Exp Eye Res 2010;91: 369-377, DOI:10.1016/j.exer.2010.06.009
2009 Meyer LM, Löfgren S, Ho Y, Lou M, Wegener A, Holz F, Söderberg PG Absence of Glutaredoxin1 (Grx1) Increases Lens Susceptibility to Oxidative Stress Induced by UVR-B. Exp Eye Res 2009;89: 833-839, DOI:10.1016/j.exer.2009.07.020
2008 Meyer LM, Söderberg PG, Dong X, Wegener A, Löfgren S Dose dependent cataractogenesis and Maximum Tolerable Dose (MTD(2.3:16)) for UVR 300 nm-induced cataract in C57BL/6J mice Exp Eye Res 2008;86: 282-289, DOI:10.1016/j.exer.2007.10.019
2007 Mody V, Kakar M, Elfving Å, Löfgren S Drinking water supplementation with ascorbate is not protective against UVR-B-induced cataract in the guinea pig. Acta Ophthalmol 2007; 86: 188-195
2007 Ayala M, Strid H, Jacobsson U, Söderberg PG p53 expression and apoptosis in the lens after ultraviolet radiation exposure. IOVS 2007; 48: 4187-4191
2007 Zhang F, Löfgren S, Söderberg PG Interaction of anesthetic drugs and UV-B irradiation in the anterior segment of the rat eye. Acta Ophthalmol 2007; 85: 745-752
2007 Dong X, Löfgren S, Ayala M, Söderberg PG Maximum tolerable dose for avoidance of cataract after repeated exposure to ultraviolet radiation in rats.. Exp Eye Res 2007; 84: 200-208
2007 Meyer LM, Söderberg PG, Dong X, Wegener A, Löfgren S Light scattering in the C57BL/6 mouse lens. Acta Ophthalmol Scand 2007; 85: 178-182
2006 Tessem M, Bathen T, Löfgren S, Mody V, Meyer LM, Dong X, Söderberg PG, Midelfart A Biological response in various compartments of the rat lens after in vivo exposure to UVR-B analyzed by HR-MAS 1H NMR spectroscopy. IOVS 2006; 47: 5404-5411
2006 Mody V, Kakar M, Elfving Å, Söderberg PG, Löfgren S Ultraviolet radiation-B-induced cataract in albino rats; maximum tolerable dose and ascorbate consumption. Acta Ophthalmol Scand 2006; 84: 390-395
2005 Dong X, Söderberg PG, Löfgren S, Ayala M Maximum tolerable dose for avoidance of cataract induced by ultraviolet radiation-B for 18 to 60 week old rats. Exp Eye Res 2005; 80: 561-566
2005 Mody V, Kakar M, Elfving Å, Söderberg PG, Ungerstedt U, Löfgren S Ascorbate in the guinea pig lens, dependence on drinking water supplementation. Acta Ophthalmol Scand 2005; 83: 228-233
2005 Mody V, Kakar M, Elfving Å, Löfgren S, Saether O Ungerstedt U Ascorbate in the rat lens, dependence on dietary intake. Ophthalmic Res 2005; 37: 142-149
2005 Ayala M, Söderberg PG Reversal of Reciprocity Failure for UVR-Induced Cataract with Vitamin E. Ophthalmic Res 2005; 37: 150-155
2005 Risa O, Saether O, Kakar M, Mody V, Löfgren S, Söderberg PG, Krane J, Midelfart A Time dependency of metabolic changes in rat lens after in vivo UVB irradiation analysed by HR-MAS 1H NMR spectroscopy. Exp Eye Res 2005; 81: 407-414
2005 Dong X, Söderberg PG, Ayala M, Löfgren S The Effect of Exposure Time on Maximum Acceptable Dose for Avoidance of Ultraviolet Radiation Induced Cataract. Ophthalmic Res 2005; 37: 197-201
2005 Meyer LM, Söderberg PG, Dong X, Wegener A UVR-B induced cataract development in C57 mice. Exp Eye Res 2005; 81: 389-394
2004 Laurell CG, Söderberg PG, Nordh L, Nordquist P Computer-simulated phacoemulsification. Ophthalmology 2004; 111: 693-698
2004 Risa O, Saether O, Löfgren S, Söderberg PG, Krane J, Midelfart A Metabolic Changes in Rat Lens after In Vivo Exposure to Ultraviolet Irradiation: Measurements by High Resolution MAS 1H NMR Spectroscopy. IOVS 2004; 45: 1916-1921
2004 Ayala M, Söderberg PG Vitamin E can protect against ultraviolet radiation-induced cataract in albino rats. Ophthalmic Res 2004; 36: 264-269
2003 Dong X, Ayala M, Söderberg PG Ultraviolet radiation induced cataract: Age and maximum acceptable dose. IOVS 2003; 44: 1150-1154
2003 Söderberg PG, Michael R, Merriam J Maximum acceptable dose of ultraviolet radiation for avoidance of cataract: A safety limit for cataract. Acta Ophthalmol 2003; 81: 165-169
2003 Löfgren S, Michael R, Söderberg PG Impact of age and sex in ultraviolet radiation cataract in rat. IOVS 2003; 44: 1629-1633
2002 Dong X, Chen E, Söderberg PG, Wang H Forceps guided nuclear cleavage cataract extraction. J Cataract and Refr Surg 2002; 28: 1320-1324
2002 Söderberg PG, Löfgren S, Ayala M, Dong X, Kakar M, Mody V Toxicity of ultraviolet radiation exposure to the lens expressed by maximum tolerable dose (MTD). Dev Ophthalmol 2002; 35: 70-75
2001 Löfgren S, Söderberg PG Lens lactate dehydrogenase inactivation after UV-B irradiation: An in vivo measure of UVR-B penetration. IOVS 2001; 42: 1833-1836
2001 Michael R, Brismar H Lens growth and protein density changes in the rat lens after in vivo exposure to ultraviolet radiation. IOVS 2001; 42: 402-408
2000 Michael R, Vrensen G, van Marle J, Löfgren S, Söderberg PG Repair in the rat lens after threshold ultraviolet radiation injury. IOVS 2000; 41: 204-212
2000 Qian W, Söderberg PG, Chen E, Magnius K, Philipson BT 3 year simvastatin treatment and lens nuclear back scattering. Br J Ophthalmol 2000; 84: 512-516
2000 Ayala M, Michael R, Söderberg PG In vivo cataract after repeated exposure to ultraviolet radiation. Exp Eye Res 2000; 70: 451-456
2000 Merriam J, Löfgren S, Michael R, Söderberg PG, Dillon J, Zheng L, Ayala M An Action Spectrum for UV-B Radiation and the Rat Lens. IOVS 2000; 41: 2642-2647
2000 Ayala M, Michael R, Söderberg PG Influence of exposure time for ultraviolet radiation induced cataract. IOVS 2000; 41: 3539-3543
2000 Qian W Angular change in backscattering of light from the human lens with nuclear cataract. Eye Nature 2000; 14: 56-60
2000 Qian W, Söderberg PG, Chen E, Philipson BT A universal opacity standard for Scheimpflug photography. Ophthalmic Res 2000; 32: 292-298
1999 Wu J, Chen E, Söderberg PG Failure of ascorbate to protect against broadband blue light-induced retinal damage in rat. Graefes Archiv Clin Exp Ophthalmol 1999; 237: 855-860
1999 Michael R, Löfgren S, Söderberg PG Lens opacities after repeated exposure to ultraviolet radiation. Acta Ophthalmol 1999; 77: 690-693
1999 Wu J, Seregard S, Spångberg B, Oskarsson M, Chen E Blue light induced apoptosis in rat retina. Eye Nature 1999; 13: 577-583
1999 Chen E, Wu J A novel device that keeps rats’ eyes open during light exposure. Lasers Light in Ophthalmology 1999; 9: 37-40
1998 Michael R, Söderberg PG, Chen E Dose-response function for lens forward light scattering after in vivo exposure to ultraviolet radiation. Graefes Archiv Clin Exp Ophthalmol 1998; 236: 625-629
1998 Löfgren S, Söderberg PG Histochemical determination of lactate dehydrogenase activity in rat lens; influence of different parameters. Acta Ophthalmol 1998; 76: 555-560
1998 Michael R, Vrensen G, Gan L, van Marle J, Söderberg PG Apoptosis in the rat lens after in vivo threshold dose ultraviolet irradiation. IOVS 1998; 13: 2681-2687
1997 Shen J, Joos K, Manns F, Ren Q, Fankhauser F II, Denham D, Söderberg PG, Parel J Ablation rate of PMMA and human cornea with a freuquency quintupled Nd:YAG laser (213 nm). Lasers Surg Med 1997; 21: 179-185
1996 Michael R, Söderberg PG, Chen E Long-term development of lens opacities after exposure to ultraviolet radiation at 300 nm. Ophthalmic Res 1996; 28: 209-218
1996 Manns F, Rol P, Parel J, Schmid A, Shen J, Matsui T, Söderberg PG Optical profilometry of poly(methylmethacrylate) surfaces after reshaping with a scanning photorefractive keratectomy (SPRK) system. Appl Optics 1996; 35: 3338-3346
1995 Chen E, Pallon J, Forslind B Distribution of calcium and sulphur in the blue-light-exposed rat retina.. Graefes Archiv Clin Exp Ophthalmol 1995; 233: 163-167
1995 Löfgren S, Söderberg PG Rat lens glycolysis after in vivo exposure to narrow band ultraviolet of blue light radiation. J Photochem Photobiol B, Biol 1995; 30: 145-151
1995 Manns F, Shen J, Söderberg PG, Matsui T Development of an algorithm for corneal reshaping with a scanning laser beam. Appl Optics 1995; 34: 4600-4608
1995 Wang L, Persson HE, Söderberg PG Receptor and neural visual readaption after flash exposure to colored flash. Acta Ophthalmol 1995; 73: 313-318
1995 Wang L, Söderberg PG Frequency and amplitude in scotopically stimulated optokinetic nystagmus. Graefes Archiv Clin Exp Ophthalmol 1995; 233: 8-12
1994 Qian W, Söderberg PG, Lindström B, Chen E, Magnius K, Philipson BT Spatial distribution of back scattering in the nuclear area of the non-cataractous human lens. Eye Nature 1994; 8: 524-529
1994 Wang L, Zand M, Söderberg PG Filter goggles imitating dark adaption for measurement of visual readaption. Acta Ophthalmol 1994; 72: 429-432
1993 Tengroth B, Fagerholm P, Söderberg PG, Hamberg-Nyström H, Epstein D Effect of Corticosteroids in Postoperative Care Following Photorefractive Keratectomies. Refr Corneal Surg 1993; 9: S61-S64
1993 Qian W, Söderberg PG, Chen E, Magnius K, Philipson BT Evaluation of gray-scale steps on Scheimpflug photographs. Acta Ophthalmol 1993; 71: 79-84
1993 Wang L, Söderberg PG, Tengroth B Measurement of visual readaption after flash exposure using optokinetic nystagmus. Acta Ophthalmol 1993; 71: 810-818
1993 Wang L, Söderberg PG Influence of target direction, intensity and velocity on horizontal optokinetic nystagmus. Acta Ophthalmol 1993; 71: 578-585
1993 Chen E Inhibition of cytochrome oxidase and blue-light damage in rat retina.. Graefes Archiv Clin Exp Ophthalmol 1993; 231: 416-423
1993 Qian W, Söderberg PG, Chen E, Magnius K, Philipson BT A common lens nuclear area in Scheimpflug photographs. Eye Nature 1993; 7: 799-804
1992 Chen E, Söderberg PG, Lindström B Cytochrome oxidase activity in rat retina after exposure to 404 nm blue light. Curr Eye Res 1992; 9: 825-831
1991 Wang L The relationship of luminous intensity and velocity for motion perception and maximum OKN elicitation. Vision Resarch 1991; 31: 1601-1609
1991 Chen E Refractive indices of the rat retinal layers. Ophthalmic Res 1991; 25: 65-68
1991 Chen E, Söderberg PG, Lindström B Lipid and protein density in the rat retina. A microradiographical study. Ophthalmic Res 1991; 23: 220-224
1991 Chen E, Chung JHC, Söderberg PG, Lindström B Microradiographical determination of dry mass content in rat retina. Ophthalmic Res 1991; 23: 33-39
1991 Söderberg PG Sodium and potassium in the lens after exposure to radiation in the 300 nm wavelength region. J Photochem Photobiol B, Biol 1991; 8: 279-294
1990 Söderberg PG Development of light dissemination in the rat lens after exposure to radiation in the 300 nm wavelength region. Ophthalmic Res 1990; 22: 271-279
1990 Söderberg PG, Lindström B Liquid scintillation counting of 3H-thymidine incorporated into rat lens DNA. App Rad Isot 1990; 41: 1-4
1990 Wang L, Goldmann P, Tengroth B Effect of spectral flash on readaption time. Aviat Space Environ Med 1990; 61: 125-32
1990 Söderberg PG, Chen E, Lindström B An objective and rapid method for the determination of light dissemination in the lens. Acta Ophthalmol 1990; 68: 44-52
1989 Chen E, Söderberg PG, Lindström B Activity distribution of cytochrome oxidase in rat retina. A quantitative histochemical study. Acta Ophthalmol 1989; 67: 645-651
1989 Söderberg PG Mass alteration in the lens after exposure to ultraviolet radiation, 300 nm. Acta Ophthalmol 1989; 67: 633-644
1989 Söderberg PG, Lindström B Determination of Na and K in the rat lens by atomic absorption spectrophotometry. Acta Ophthalmol 1989; 67: 582-592
1989 Chen E, Söderberg PG, McKerrel AD, Tengroth B, Lindström B Inactivation of lactate dehydrogenase by UV radiation in the 300 nm wavelength region. Radiat Environ Biophys 1989; 28: 185-191
1988 Söderberg PG Acute cataract in the rat after exposure to radiation in the 300 nm wavelength region, a study of the macro-, micro- and ultrastructure. Acta Ophthalmol 1988; 66: 141-152
1987 Bergmanson JPG, Söderberg PG, Estrada PA A comparison between the measured and the desirable quality of hydrogel extended wear contact lenses. Acta Ophthalmol 1987; 65: 417-423
1986 Bergmanson JPG, Söderberg PG, Philipson BT Progressive microstructural changes in the closed system incubated lens. Acta Ophthalmol 1986; 64: 312-317
1986 Söderberg PG, Philipson BT, Lindström B Unscheduled DNA synthesis in lens epithelium after in vivo exposure to UV radiation in the 300 nm wavelength region. Acta Ophthalmol 1986; 64: 162-168
1985 Bergmanson JPG, Johnson J, Söderberg PG, Philipson BT Lactate levels in the rabbit cornea and aqueous humour subsequent to non-gas permeable contact lens wear. Cornea 1985; 4: 173-176